Senior Project Associate Job at THSTI For MSc/PhD Bioinformatics

THSTI Bioinformatics Project Vacancy Opening – MSc & PhD Candidates Apply

The THSTI Bioinformatics Project Vacancy Opening presents an exciting opportunity for individuals with a background in Bioinformatics to engage in impactful research, contribute to the field of Metabolic associated liver disease, and work towards the discovery of disease and progression biomarkers in MAFLD for improved clinical outcomes. THSTI invites job applications from individuals with an MSc/PhD qualification in the field of Bioinformatics. check below for detailed information.

This job expires in

Rolling Recruitment Notice No. : THS/RN/01/2023/06-II
VACANCY NOTIFICATION

Name of the post: Senior Project Associate

No. of posts: one 

Project: Metabolic associated liver disease (MAFLD) in lean and obese: search for disease and progression biomarker

Age limit: 40

GENERAL TERMS & CONDITIONS:

1. This is a short-term position and extension will be granted subject to satisfactory performance of the incumbent and tenure of the project for which he/she is selected. The person appointed to this position will not have any claim for regularization of his/her employment.
2. All educational, professional and technical qualification should be from a recognized Board/University.
3. The experience requirement specified above shall be the experience acquired after obtaining the minimum educational qualifications specified for the post.
4. Closing date of online application will be the CRUCIAL DATE for determining eligibility with regard to age, essential qualification etc.
5. The age limit, qualification, experience and other requirements may be relaxed at the discretion of the competent authority, in case of candidates who are otherwise suitable. In case candidates are not found suitable for the posts notified, they can be offered lower post/ lower emoluments on the recommendation of the Selection Committee.
6. Age and other relaxations for direct recruits and departmental candidates: 1. By five years for candidates belonging to SC/ST communities. 2. By three years for candidates belonging to OBC communities. 3. For Persons with Benchmark Disabilities (PwBD) falling under the following categories : (i) UR – ten years, ii) OBC – 13 years (iii) SC/ST-15 4. Age is relax able for Central Government servants up to five years in accordance with the instructions or orders issued by the Central Government, from time-to-time. 5. There is no upper age limit for the Institute employees who are treated as departmental candidates. 6. For Ex-servicemen upto the extent of service rendered in defense forces (Army, Navy & Air force) plus 3 years provided they have put in a minimum of 6 months attested service.
7. In case a large number of applications are received, screening will be done to limit the number of candidates to those possessing higher/relevant qualification and experience.
8. Number of positions may vary depending upon the requirement at the time of interview.
9. All results/notifications will only be published on our website. Therefore, the candidates should visit the THSTI website regularly.
10. With regard to any provisions not covered in this notification, the bye laws of THSTI / Govt. of India rules / guidelines shall prevail.
11. All communications will only be made through email.
12. Canvassing wrong information in any form will be a disqualification

HOW TO APPLY:

1. Documents to be kept handy before filling up the online application: (all the documents except (i) should be in pdf format):
   i) A soft copy of your passport size photo and signature. (jpeg/jpg/png format)
   ii) A comprehensive CV containing details of qualification, positions held, professional experience / distinctions etc.
   iii) Matriculation certificate (equivalent to 10th Standard) / Mark sheet
   iv) Intermediate certificate (equivalent to 12th Standard) / Mark sheet
   v) Graduation degree certificate / Mark sheet
   vi) Post-Graduation degree certificate & Mark sheet
   vii) Ph.D or equivalent degree certificate (if applicable)
   viii) Relevant experience certificates (if applicable)
   ix) Caste / Disability certificate in the format prescribed by the Govt. of India.

Procedure for filling up online application:

i) The eligible and interested candidates may apply online at the Institute’s website www.thsti.res.in/career. Applications through any other mode will not be accepted.
ii) The following will be the stepwise procedure
A) Step 1 : Details of applicant
B) Step 2 : Uploading of documents
C) Step 3 : Payment of application fee

• The payment can be made by using Debit Card / Credit Card / Internet Banking/ UPI.
• Once payment is made, no correction / modification is possible
• Candidates are requested to keep a copy of the provisional receipt for future reference.
• Fees once paid shall not be refunded under any circumstances.

Details of fees to be paid are as shown below:

 1. Unreserved, OBC & EWS candidates Rs 236/-                                                               2. SC/ST/Women/PwBD Rs 118/-

D) Step 4 : Submission of application form

iii) On successful submission of application, an auto-generated email containing the reference number will be sent to the email address provided. Please keep a note of the reference number for future correspondence.
iv) Candidates are required to keep a printout of the online application form by using the print button on the dashboard for future reference.
v) Candidates must ensure that he / she fulfills all the eligibility criteria as stipulated in the advertisement. If it is found that he / she does not fulfill the stipulated criteria during the recruitment process, the candidature of the candidate will be canceled. If the same is noticed after the appointment, the candidate will be terminated following due process.
vi) Incomplete applications shall be summarily rejected and no correspondence in this regard shall be entertained.
vii) In case of difficulty in filling up the online form, please send e-mail to [email protected] along with the screenshot of the error displayed (if any).

• Last date for receipt of online application: 10th July 2023.
• The applications will be scrutinised/shortlisted and processed for further selection.

Minimum Qualification and Experience: Master’s degree in Bioinformatics/ Computer Science or associated fields from a recognized University with four years of post-qualification experience in R&D. OR PhD in Biological Sciences/ Bioinformatics or associated fields. 

Desirable Qualification & Experience: Expertise in high-throughput data analysis for Proteomics/metabolomics/lipidomics (LCMS based). Statistical analysis of data using R, python or Perl

Monthly Emoluments: Rs. 42,000/- +HRA

Check the notification below

Possible interview questions along with their answers that might be asked for MSc/PhD in Bioinformatics job at THSTI as a Senior Project Associate position   

1. Question: Can you provide an overview of your experience in high-throughput data analysis for Proteomics/metabolomics/lipidomics?

Answer: Certainly. I have extensive experience in analyzing high-throughput data in the field of Proteomics/metabolomics/lipidomics, particularly using LCMS-based techniques. I have worked on several projects where I have processed and analyzed large datasets to identify biomarkers and understand disease mechanisms. I am proficient in using software such as R, Python, and Perl for statistical analysis and have a strong background in data mining and interpretation.

2. Question: How would you handle the challenges associated with analyzing large datasets in a time-sensitive research project?

Answer: When dealing with large datasets in a time-sensitive project, it is crucial to have a systematic approach. Firstly, I would prioritize data preprocessing and quality control to ensure accurate and reliable results. Then, I would utilize parallel computing techniques or distributed computing resources to expedite the analysis process. Additionally, I would optimize code and workflows to improve efficiency and leverage automation wherever possible. Regular progress monitoring and effective communication with the team would also help identify and address any potential bottlenecks.

3. Question: Can you provide an example of a research project where you applied statistical analysis using R, Python, or Perl?

Answer: Certainly. In a recent project, I investigated the association between specific metabolites and a disease outcome. I performed statistical analysis using R, where I employed various techniques such as t-tests, ANOVA, and regression models to assess the significance of metabolite variations across different groups. I also implemented data visualization techniques to present the results effectively. The statistical analysis provided valuable insights into the underlying mechanisms of the disease and helped identify potential biomarkers for further investigation.

4. Question: How would you approach the identification of disease and progression biomarkers in the context of Metabolic associated liver disease (MAFLD) in lean and obese individuals?

Answer: To identify disease and progression biomarkers in MAFLD, I would adopt a comprehensive approach. Firstly, I would analyze large-scale proteomics/metabolomics/lipidomics data obtained from lean and obese individuals using LCMS techniques. I would apply statistical methods to identify differentially expressed molecules between the two groups. Subsequently, I would perform pathway analysis and network analysis to understand the underlying biological processes and interactions. I would also consider integrating multi-omics data, if available, to enhance the accuracy of biomarker discovery. Finally, I would validate the identified biomarkers through appropriate experimental assays to confirm their association with disease and progression.

5. Question: How do you stay updated with the latest advancements and trends in the field of Bioinformatics and associated areas?

Answer: As a professional in the field of Bioinformatics, I understand the importance of staying updated with the latest advancements and trends. I regularly attend conferences, workshops, and seminars relevant to my field of expertise. I also actively participate in online forums and discussion groups where experts share their insights and findings. Additionally, I subscribe to scientific journals and publications to keep myself informed about the most recent research publications. Continuous learning and exploring new technologies and methodologies are essential aspects of my professional development, and I strive to stay updated with the rapidly evolving field of Bioinformatics.

Editor’s Note: THSTI Bioinformatics Project Vacancy 2023. THSTI Bioinformatics Project Vacancy – MSc & PhD Candidates Apply. Please ensure you are subscribed to the Biotecnika Times Newsletter and our YouTube channel to be notified of the latest industry news. Follow us on social media like Twitter, Telegram, Facebook and Instagram.