Schrödinger Bioinformatics Job Opening For PhD Candidates, Apply Online
Schrödinger Bioinformatics Job Opening For PhD Candidates, Apply Online. PhD Bioinformatics candidates are eligible to apply for the Applications Scientist vacancy at Schrödinger. Check details below
Possible Interview Questions for the Applications Scientist Role are posted below.
Applications Scientist
We’re looking to hire an Applications Scientist to join us in our mission to improve human health and quality of life through the development, distribution, and application of advanced computational methods.
Schrödinger is on the cutting edge of computer-aided drug discovery and materials science. We set the record for the largest and fastest cloud computing run, and our software suites continue to revolutionize the design of therapeutics and materials. FEP+, WaterMap, Glide, Maestro, and LiveDesign are just a few examples of the tools we’ve created.
As a member of the India Applications Science team, you’ll provide scientific support for customers ranging from large pharmas to biotechs, as well as academic institutions. Alongside your fellow Applications Scientists, you’ll provide guidance to our life science customers and help them to tackle various challenging drug discovery problems.
Who will love this job:
- A computer-aided design enthusiast (both in theory and application) – specifically, someone with solid experience in structure-based drug design
- An excellent communicator and presenter with superb organizational skills
- A dedicated scientist interested in advancing drug discovery research
- A creative person who enjoys helping others solve problems
- A self-motivated team player who thrives in a cross-functional environment
What you’ll do:
- Provide scientific support to current and prospective customers, which includes demonstrating the optimal use of our life science software suites, facilitating interactions between customers and product development teams, and providing general scientific guidance
- Engage in cutting edge scientific research to continuously develop personal expertise and establish best practices for customers
- Work cross-functionally with Product Managers, Account Managers and the Marketing team to improve business strategies
- Publish scientific papers and present at conferences
What you should have:
- PhD in computational chemistry, bioinformatics, or a related field with 2-4 years of experience
- Post-doctoral research and/or relevant experience in the commercial sector
- A solid understanding of the drug discovery process
- Experience in one of the following: structure-based drug design, molecular dynamics simulations/enhanced sampling/free energy calculation methods, ligand-based drug design, chemoinformatics, quantum mechanics, and/or structural modelling
- Willingness to travel
- Python programming experience and medicinal chemistry knowledge are a plus
Possible Interview Questions for the Applications Scientist Role:
- Can you explain your experience in structure-based drug design? How have you utilized computational methods in this field?
- Answer: In my previous role, I focused on structure-based drug design by leveraging computational techniques to analyze protein-ligand interactions and identify potential drug candidates. I used tools like molecular docking and virtual screening to optimize lead compounds and prioritize their efficacy.
- How have you provided scientific support to customers in the past? Give an example of a challenging drug discovery problem you helped solve.
- Answer: In my previous position, I collaborated with a pharmaceutical company facing difficulties in optimizing a specific compound’s binding affinity. By employing molecular dynamics simulations and free energy calculations, I identified critical interactions and proposed modifications that significantly improved the compound’s potency.
- Can you share your experience in engaging in scientific research and establishing best practices for customers?
- Answer: During my post-doctoral research, I focused on developing novel computational methods for predicting protein-ligand binding affinities. By staying up-to-date with the latest advancements in the field and actively participating in scientific conferences, I gained insights into cutting-edge techniques and established best practices that I could share with customers.
- How would you collaborate with cross-functional teams, such as Product Managers and Account Managers, to improve business strategies?
- Answer: As an Applications Scientist, I understand the importance of collaboration across teams. I would actively communicate with Product Managers to provide feedback on software enhancements based on customer needs. Additionally, I would work closely with Account Managers to identify potential areas of growth and contribute to the development of tailored solutions for customers.
- Have you published scientific papers or presented at conferences? Can you highlight any notable contributions in your field?
- Answer: Yes, I have published several scientific papers in reputable journals and presented my research findings at international conferences. One notable contribution was the development of a novel scoring function for virtual screening, which improved the accuracy of hit identification in early-stage drug discovery. This work was well-received by the scientific community and has been cited by other researchers in the field.
Note: The answers provided are general examples and can be tailored based on the candidate’s specific experiences and achievements.
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