Why Fetus Is Not An Antigen For Mothers Immune System?
Voice of Biotecnika
Have you ever wondered why a Mothers Immune System does not reject Developing Fetus As a Foreign tissue? Our body has an amazing defense mechanism against foreign bodies, the immune system, but why isn’t fetus rejected, that is semi-allogenic to the mother? Today is this Podcast we are going to unravel the mystery behind Why Fetus Is Not Treated As An Antigen – the fascinating facts of our Body’s Immune system.
Fetus developing inside host faces many challenges to overcome, One could, therefore, speculate that the innate immune system at the feto-maternal interface undergoes less stringent selective pressures to ensure quick and efficient local protection against infection, while the adaptive immune system had to remain under full control to prevent rejection of the semi-allogeneic fetus. A central feature of the body’s natural immune defense against transplanted tissue and pathogen is the production of chemokines that initiates a local inflammatory response. During y, although the foreign antigens of the fetus and the placenta are in direct contact with the maternal immune system, fail to elicit any response. Listen more in the podcast below: