Application for Junior Research Fellow in DBT funded project for 3 years
Applications are invited for the following post of Junior Research Fellow (temporary position coterminous with the project) under DBT funded research project on “Understanding the functional role of ser/thr phosphatase PHLPP in inflammation/ER stress induced insulin resistance”
Job Title : Junior Research Fellow
Fellowship : Rs. 25,000 plus 30% HRA (total Rs. 32,500) per month for first two years and Rs. 28,000 plus 30% HRA (total Rs. 36,400) per month for 3rd year
Duration: The duration of the fellowship is for three years. However, the performance of the candidate will be rigorously reviewed every 6 months and the fellowship will be renewed only upon satisfactory performance.
Responsibilities:
1) Literature search.
2) Design, plan and execute experiments under the supervision of the scientist.
3) Provide scientific support to the scientist in his research activities.
4) Book keeping and maintenance of stocks and consumables.
Essential Qualifications:
A) Required:
1) Post-graduate degree in Biotechnology or any other related branch of Basic Sciences from a recognized university/institute with CSIR NET qualification.
OR Graduate degree in a Professional course from a recognized university/institute with CSIR NET qualification OR Post-graduate degree in a Professional
2) Candidate should demonstrate consistent academic record of minimum 60% aggregate in all qualifying examinations.
3) The candidate should be motivated and committed.
B) Desirable : Expertise/experience in Molecular Biology and Cell biology.
C) Experience: 1-2 years in the areas of Molecular Biology and Cell biology.
D) Preferable: Relevant research experience as evident from thesis/dissertation/project work.
Project summary:
Sub-optimal response to insulin termed as insulin resistance is a hallmark of type 2 diabetes and is evident decades before frank hyperglycemia is observed. Obesity activates ER stress and inflammatory pathways that cause insulin resistance. The mechanisms governing ER stress and inflammation induced insulin resistance are far from being understood. Emerging reports suggest that cross-talk exists between ER stress and inflammation. However, how ER stress, inflammation and metabolic responses are integrated is not well understood. PHLPP belongs to a novel family of Ser/Thr phosphatases and was identified in 2005 from a database search of human genome for a phosphatase linked to a pleckstrin homology (PH) domain. The goal of this project is to examine the functional importance of PHLPP in controlling in ER stress/inflammation mediated skeletal muscle insulin resistance.
How to Apply :
Qualified and interested candidates may send their curriculum vitae by e-mail to [email protected] on or before 22nd January 2018 with “DBT-PHLPP Project” as the subject line of the email. There will be two rounds of interview. Shortlisted candidates will be first interviewed through skype/telecon followed by a personal interview at Dr. Reddy’s Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad.
