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Bioinformatics Summer Internship 2024 With Hands-On-Training + Project / Dissertation - 30 Days, 3 Months & 6 Months Duration

Aurobindo Pharma Ltd (APL). APL is a growing Indian multinational pharmaceutical manufacturing firm with turnover of over US$650Mn, with presence in more than 22 countries across the globe. APL produces a wide range of Active Pharmaceutical Ingredients (API’s) and Finished Formulations which is marketed in more than 108 countries across the globe

Job Title:  Cell Science – Upstream Process Development for Biologics

No of Posts: 6

Location: Hyderabad / Secunderabad

Eligibility: B.sc / M.sc Life science, Biotechnology

Experience : 1-6 years experience

Job Description:

  • The candidates applying for the job must have had experience handling at least two mAbs, having contributed towards developing a cell culture upstream process that was used either in generating clinical material and/or material for commercial use
  • Contribute towards drafting relevant CMC sections as part of CTD preparation/submissions
  • Hands on experience in aseptic and sterility techniques, vial thawing and cell banking procedures is required
  • The candidate must have strong analytical and problem solving skills to optimize and troubleshoot upstream processes
  • Experience in trouble shooting bioreactor control systems, using cell counters and biochemistry analyzers is essential
  • Knowledge of process control, PID paradigms and instrumentation clusters is required
  • The candidate is expected to have sound knowledge in Numerical Methods of Integration, mass and material balances, stoichiometric kinetics and mathematical evaluation of cell metabolism, mass transfer and nutrients uptake effects
  • Must have high attention to detail, excellent communication skills (both oral and written), and the ability to work independently on bioreactors with minimal supervision
  • Experience in scaling up and scaling down bioreactor processes between 1000 to 5 L scales will be helpful
  • Experience in DoE for early stage screening of clones, clones-media combinations, chalking out feeding regimes and the interplay with other cell culture process development levers is desired
  • Working knowledge of BSL2 safety norms, culturing and inactivating GMOs for safe disposal is essential
  • Performing daily maintenance duties involving preparation of media and stock solutions, research-cell-banks, sterilization, and bioreactors maintenance

Apply Here

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