Biocon Biologics R&D Bioassay Development Lab Role – Life Sciences, Biotech, Biochem Apply Online
Research & Development: Opportunities in Bioassay Development Lab
Bengaluru, Karnataka, India
About the job
Biocon Biologics is a fully-integrated ‘pure play’ biosimilars organization globally committed towards transforming patient lives through innovative and inclusive healthcare solutions. It is engaged in developing high-quality, affordable biosimilars aimed at expanding patient access to cutting-edge class of therapies across the world. Biocon Biologics is a subsidiary of Biocon Ltd, an innovation led-global biopharmaceuticals company and India’s first publicly listed biotech enterprise. Biocon Biologics has one of the largest biosimilars portfolios, a wide global footprint, state-of-the-art manufacturing facilities, world-class R&D ecosystem, and high quality & compliance standards, enabling it to fulfil unmet needs of patients across the globe.
Role Details –
- Relevant experience in biopharmaceutical industry in proof-of-concept studies, bioassay method development/qualification/transfer, stability sample testing, CQA assessment, biosimilarity analysis of monoclonal antibodies, insulin analogues, pegylated proteins, antibody-drug conjugates, therapeutic peptides.
- Knowledge on ICH, USP and WHO guidelines, systems biology, and its relevance to drug development in biopharmaceutical industry.
- Proficiency with aseptic technique of handling tissue culture model.
- Thorough understanding of cell culture and hands-on experience with in vitro bioassay techniques and their applications in cellular signalling, receptor binding, cytokine secretion, cell proliferation, cytotoxicity, antibody effector function and immune assays.
- Experience with novel technologies (including but not limited to HTRF/AlphaLISA, Luminescence, ELISA, Flow Cytometry, SPR, BLI)
- Proficiency in handling instruments like (Plate Reader, Flow Cytometer, Biacore, Octet) and familiarization with 96, 384 well formats of assay
- Independently design, execute and record experiments in electronic lab note-book (Labware-LIMS) following ALCOA principles.
- Interpret and analyse data using relevant instrument software, and disseminate results through reports, data presentations in team meetings. Able to troubleshoot critical issues and determine possible solutions.
- Maintain instruments in coordination with operations team and support installation of new instrument. Keep track of ordering and maintaining inventory of consumables/reagents and support in lab maintenance.
- Familiarity with statistical tools (GraphPad Prism, JMP), Document Management System (DMS), Digital Quality Management Software (Trackwise) is desired.
- Author or review documents including method development reports, protocols (qualification/transfer/study) and reports (qualification/transfer/study). Prepare operating procedures (IOP, EOP, SOP) and author change controls, deviation and CAPA
- Work primarily as an individual contributor and train and cross-train colleagues towards experimental design, execution, and troubleshooting; technical review of raw data.
Education & Experience –
- Post-graduate with 5-7 years of experience or PhD with 1-2 years of experience in biopharmaceutical industry.
- Life sciences background in biochemistry, biotechnology, or allied subjects preferred.
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