Syngene PhD Immunology

Syngene PhD Immunology, Cell Biology Research Job – Apply Online

Syngene PhD Immunology, Cell Biology Research Job – Apply Online. PhD Immunology, Oncology and Cell Biology candidates apply for Senior Research Investigator/Research Investigator- Translational Medicine-Clinical Flow Cytometry at Syngene. Interested candidates can check the details below and apply for the role of Senior Research Investigator at Syngene.

Designation: Senior Research Investigator/Research Investigator- Translational Medicine-Clinical Flow Cytometry

Requisition ID: 54613

Job Location: Bangalore

Department: TM-TSDX- Clinical Flow Cytometry

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose:

This position is within the clinical flow cytometry team of Translational Medicine (TM) at BBRC, Syngene. You will play a key role in drug discovery

and clinical development by providing technical expertise for design, execution and results interpretation of high order multicolor flow cytometry assays. Provide subject matter expertise to programs. Work in a collaborative manner with internal and external stakeholders to enable program transition to the next stage. Execute and oversee assay development, validation, instrument calibration/quality assurance and maintenance of the flow cytometers. Support clinical sample analysis. Develop new capabilities in high order flow cytometry to support the development of biomarker assays as per program needs. Day to day oversight and management of team of scientists.

Key Responsibilities:

  • Collaborate with program leads to understand requirements and support project needs
  • Provide technical expertise for design and execution of flow cytometry assays at the lab bench
  • Perform assay development and validation
  • Oversee clinical sample analysis and data interpretation
  • Deliver on projects within timelines
  • Oversee maintenance and calibration of flow cytometers
  • Lead a team of 1-3 Scientists and oversee their day to day activities
  • Establish advanced flow cytometry capabilities in the team
  • Lead exploratory research projects

Educational Qualification and Experience:

PhD in Immunology/Oncology/ Heme malignancies/Cell biology or related disciplines with 1-6 years related experience working on high order multicolor flow cytometry assays in industry/academic research.

Technical/Functional Skills:

  • Background and expertise in Immunology/Cell Biology/Molecular Biology/ Biochemistry/ Oncology/Heme malignancies
  • Experienced in design, execution and data interpretation of multicolor flow cytometry assays (required)
  • Experience working on diverse flow cytometer instruments. Demonstrated capability of working on research projects and delivering under tight timelines
  • Experience with third party flow cytometry data analysis softwares (eg: Flowjo, FCS express, etc)
  • Experience working in drug discovery will be a plus
  • Excellent publication record and demonstrated ability for independent research
  • Having worked with human clinical samples is desired
  • Statistical skills and understanding of experimental design
  • Familiarity with unsupervised flow cytometry data analysis tools will be considered a plus .Usage of scientific softwares like graphpad prism or equivalent
  • Research oriented mindset

Experience:

1-6 years of prior experience in industry or academic institutes with exposure to flow cytometry technology

Behavioural Skills:

  • Excellent communication and presentation skills
  • Ability to work collaboratively as part of a multi-disciplinary team Ability to adapt to dynamic work environment
  • Strong analytical and troubleshooting skills
  • Good documentation skill set
  • Team player and able to adapt to a fast changing work environment

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.

Send your CV to: [email protected].

Here are some interview questions with answers related to the job role of Senior Research Investigator at Syngene:

1. Can you describe your experience in designing and executing multicolour flow cytometry assays for drug discovery and clinical development? Answer: During my previous roles in both industry and academia, I have gained extensive experience in designing and executing high order multicolor flow cytometry assays. I have worked on diverse flow cytometer instruments and have a strong track record of delivering projects within tight timelines. My expertise in immunology, cell biology, and oncology has allowed me to interpret data effectively, which has contributed to a successful publication record. Additionally, I am familiar with third-party flow cytometry data analysis software like FlowJo and FCS Express, which further enhances my capabilities in this field.

2. How do you approach the validation and development of new flow cytometry assays for clinical sample analysis? Answer: Validating and developing new flow cytometry assays requires a systematic approach. I begin by thoroughly understanding the project requirements and collaborating with program leads to ensure alignment. Then, I design the assays at the lab bench, keeping in mind the specific clinical sample types and objectives. During the development process, I carefully optimize the assay conditions, and once established, I perform validation experiments to ensure accuracy and reproducibility. Regular maintenance and calibration of flow cytometers are essential to maintain data integrity and consistency throughout the analysis.

3. In this role, you will be leading a team of scientists. How do you plan to manage and motivate your team effectively? Answer: As a team leader, I believe in fostering a collaborative and supportive work environment. My approach includes providing clear goals and expectations to team members and encouraging open communication. I will ensure that each team member’s skills and strengths are utilized effectively in different projects. Regular one-on-one meetings will be conducted to address any challenges they may face and to provide constructive feedback. Recognizing and appreciating their efforts will be essential to keep the team motivated and engaged. Additionally, I will lead by example, demonstrating a strong work ethic and a passion for scientific research.

4. Can you share an example of a challenging project you worked on involving flow cytometry, and how you successfully managed to deliver results within tight timelines? Answer: Certainly! In my previous role, I was involved in a time-sensitive drug discovery project that required the development of a novel multicolor flow cytometry assay. The project demanded quick decision-making and adaptability to changing requirements. To meet the tight timelines, I formed a highly efficient team, dividing tasks based on individual strengths and expertise. We adopted a collaborative approach, where frequent meetings and open discussions allowed us to address challenges promptly. I personally ensured that all instruments were well-calibrated and maintained to minimize any technical issues. Thanks to our concerted efforts, we successfully delivered accurate and reproducible results, contributing to the project’s advancement and subsequent publication in a reputable journal.

ALL THE BEST!

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