Cell Biology Research Assistant Job at Tata Translational Cancer Research Centre

Research Assistant Job at Tata Translational Cancer Research Centre

Research Assistant Job at Tata Translational Cancer Research Centre. MSc Biological Sciences  Job at Tata Translational Cancer Research Centre. Biological Sciences jobs. Check out all of the details on the same below

The five possible interview questions that can be asked in the technical round for the Research Assistant position in Cell Biology at Tata Translational Cancer Research Centre are posted below

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TATA MEMORIAL HOSPITAL
[TATA MEMORIAL CENTRE]
H.R.D. DEPARTMENT
(Grant-In-Aid Institute of Department of Atomic Energy, Government of India)

Name of Post – Research Assistant in Cell Biology

No. of Posts – 01

Appointing Organization – Tata Translational Cancer Research Centre
Tata Medical Center, Kolkata

The Tata Medical Center and the Tata Translational Cancer Research Centre –

Tata Medical Center (TMC) is a multispecialty institution for tertiary cancer care based in New Town, Kolkata. At TMC, clinical and research activities are integrated to provide state-of-the-art care for patients with cancer. This integration is enabled by the Tata Translational Cancer Research Centre (TTCRC), the research arm of TMC. TTCRC is within a dedicated academic space and spread over 3 floors. At TTCRC, a multidisciplinary

team of clinicians, scientists, academics and industry professionals collaborate to develop a systems medicine approach in cancer research. This approach is focussed on developing innovative, indigenous, cost-effective and equitable strategies to improve cancer diagnosis; develop treatments that match disease characteristics and are adapted to treatment response; and, identify prognostic and predictive disease biomarkers. These strategies are multi-dimensional and involve an iterative pathway that include clinical studies, high-throughput laboratory investigations, computational strategies to integrate, analyse and model data, hypothesis-based pre-clinical studies and evidence-based translation of findings to clinical practice. For additional information on work at TTCRC, visit the website: https://www.ttcrc.org/.

The Position –

In this position, you will work as part of the cancer cell biology group at TTCRC. The group uses high-throughput discovery screens coupled with systematic hypothesis-driven studies to investigate potential leads from clinical observations and proteogenomic studies. Integral to this approach is the development of suitable pre-clinical tumour models that closely recapitulate disease and that are robust and reproducible. The group is supported by a dedicated tissue biorepository, a clinical research unit, genomics and informatics analyses. Access to resources include high-throughput microscopy, flow cytometry, dedicated tissue culture facility, virus transduction facility and mass spectroscopy. Your primary responsibility will be to continue, optimise and extend ongoing work on developing, establishing and maintaining suitable primary cultures from tissue samples. This will involve working closely with the hospital’s multidisciplinary clinical service, the tissue biorepository unit and colleagues in the cancer cell biology group. You will also participate in downstream functional studies that will use these model cell systems to investigate disease biology and identify therapeutic opportunities. The post holder will have a designated desk and computer.

How to Apply–

Appointment and Reporting

Appointment to the position will initially be for 3 (three) years. The consolidated monthly salary will be based on a review of qualifications and experience. The first year is probationary Confirmation in the position and progression to years 2 and 3 is subject to a satisfactory review of performance through periodic appraisals of performance. Appraisals will also determine salary increments and promotions. The successful applicant will be managed by the Lead Scientist in Cell Biology and will report to the Director.

Enquiries

• For further details on TMC and TTCRC, visit www.tmckolkata.com.
• Submission of applications by post or by e-mail to:
  Mr. Suvasish Mukherjee;
  Head, Human Resources; Tata Medical Center;
  14 Major Arterial Road (East-West); Newtown, Rajarhat;
  Kolkata 700 160
  e-mail: [email protected].
• For informal enquiries,
  Satadru Dey, e-mail: [email protected].

Last date of Application: 17/6/2023

Minimum required qualifications/experience –

(a) MSc in Biological Sciences, including Life Sciences, Biotechnology, Cell & Molecular Biology, Biochemistry, Microbiology and Pharmacology
(b) Minimum 6 months of experience with mammalian cell culture techniques
(c) Familiarity with DNA, RNA and protein extraction techniques, qRT-PCR and Western Blot
(d) Familiarity with basic research laboratory protocols, procedures and techniques

Necessary qualities

(a) Integrity, perseverance, enthusiasm
(b) Focus and commitment in carrying out tasks and duties
(c) Critical analytical and problem-solving skills, capable of independent work
(d) Ability to work effectively as part of a multidisciplinary team
(e) Clarity in career and professional development goals

Job-related knowledge / Aptitude, skills, etc.	Requirements	Essential / Desirable	How identified
1. Disposition / Attitude / Work habits	a. Integrity b. Flexibility c. Motivated d. Committed e. Willing to learn new skills f. Works as part of a team g. Receptive to new ideas h. Capable of independent work & to an agreed plan i. Good time management j. Organised, able to prioritise responsibilities k. Works to high technical and quality standards l. Be willing to stay with us for at least 2 years	a. Essential b. Essential c. Essential d. Essential e. Essential f. Essential g. Essential h. Essential i. Essential j. Essential k. Essential l. Essential	Application form CV Profile Interview References
2. Education / Qualifications	MSc in Biological Sciences, (Life Sciences, Biotechnology, Cell & Molecular Biology, Microbiology& Pharmacology)	Essential	Interview Application form CV
3. Experience in research	a. Good laboratory practice b. Cell & molecular biology techniques, protocols	a. Essential b. Essential	Application form CV Interview & References
4. Skills and Ability	a. Critical thinking b. Problem solving skills c. Readiness to evaluate, develop and test new approaches and strategies	a. Essential b. Essential c. Essential	Application form CV Interview References

 

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Here are five possible interview questions that can be asked in the technical round for the Research Assistant position in Cell Biology at Tata Translational Cancer Research Centre:

1. Can you describe your experience with mammalian cell culture techniques? Provide an example of a project or experiment where you utilized these techniques.
   • Answer: During my previous research experience, I worked extensively with mammalian cell cultures. I have hands-on experience in maintaining various cell lines, subculturing, and optimizing growth conditions. In one project, we investigated the effect of a specific compound on cell proliferation by treating different cell lines and monitoring their growth using various assays. I successfully established stable cell cultures and performed functional studies to evaluate the compound’s impact on cell viability.
2. Familiarity with DNA, RNA, and protein extraction techniques, as well as qRT-PCR and Western Blot, is mentioned as a requirement. Can you provide examples of your experience using these techniques in a research setting?
   • Answer: I have a strong background in molecular biology techniques. In my previous research project, we aimed to understand the gene expression changes in response to a particular treatment. I extracted RNA from the cells using the TRIzol method, performed reverse transcription to synthesize cDNA, and quantified the expression levels of target genes using qRT-PCR. Additionally, I have experience in protein extraction and purification methods, including Western Blot analysis, to investigate protein expression and signaling pathways.
3. The job description emphasizes working as part of a multidisciplinary team. Can you provide an example of a project where you collaborated with individuals from different disciplines and how you effectively contributed to the team’s goals?
   • Answer: Collaboration is essential in scientific research, and I have experience working in multidisciplinary teams. In a recent project, we aimed to develop a new drug delivery system using nanoparticles. As part of the team, I collaborated with chemists, material scientists, and pharmacologists. I contributed my expertise in cell biology to evaluate the nanoparticles’ internalization, cytotoxicity, and drug release kinetics. By integrating our knowledge and skills, we successfully developed a promising drug delivery platform with improved efficacy and reduced side effects.
4. Critical thinking and problem-solving skills are mentioned as necessary qualities. Can you provide an example of a challenging problem or obstacle you encountered during your research and how you approached solving it?
   • Answer: In my previous research, I encountered difficulties in optimizing a specific assay to measure protein-protein interactions. Despite following established protocols, I was not obtaining reliable results. To overcome this challenge, I reviewed the literature, consulted with colleagues, and attended scientific conferences to explore alternative approaches. Eventually, I modified the assay conditions, performed additional controls, and optimized the experimental parameters. These efforts resulted in improved data quality and helped advance our understanding of the protein interactions under investigation.
5. The job description highlights the importance of clarity in career and professional development goals. Can you elaborate on your long-term career aspirations and how this position aligns with your goals?
   • Answer: As someone passionate about cancer research and translational medicine, my long-term goal is to contribute to the development of innovative cancer therapies that can improve patient outcomes. This position as a Research Assistant in Cell Biology at Tata Translational Cancer Research Centre aligns perfectly with my aspirations. I am eager to work in a multidisciplinary environment, collaborate with experts in the field, and contribute to cutting-edge research focused on understanding disease biology and identifying therapeutic opportunities. I believe this opportunity will provide me with the necessary skills and knowledge to progress towards my long-term career goals.

Remember to tailor your answers based on your own experiences, skills, and aspirations. Good luck with your interview!

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