Bioinformatics Facility At ACBR Generates
Novel Potentials Drug Targets
At Dr. B.R. Ambedkar Center for Biomedical Research (ACBR), New Delhi, funded by the Department Of Biotechnology, the bioinformatics center has used bioinformatics and computational drug design effectively for identifying drug targets, for guiding the design of novel potential drug molecules, and for assisting bench experiments, in addition to the analysis of a large amount of data available in the public domain to derive novel pathways through network analysis.
Many potential novel drug targets, particularly epigenetic drugs and combinatorial therapy combining classical cell division regulators and many promising leads have been provided by the work done at the center. For an in-depth understanding of drug resistance in Neisseria gonorrhoeae, the Bioinformatics Facility (BIF) has been utilized under the infectious disease area. Additionally, for genome mining for novel epigenetic regulatory tool-kit of the human genome, the BIF has been utilized. This has yielded both novel cis-elements and also novel functions for known epigenetic modifiers.
Patent Granted: A new Fluorescent Beacon probe-based diagnostic Tool/Kit for molecular detection of Translocation t(9;22)/ BCR – ABL1 in Leukemic patients and Method of
Societal impact:
- In clinical practice and health-related policymaking, responsible and transparent dissemination of research findings and implementation.
- Development of Diagnostic kits for sexually transmitted diseases at affordable prices.
- Delivering lectures at health conferences and symposia to increase community awareness about diseases.
- Setting of future research priorities through finding newer ways to combat diseases,
identifying targets, studying genetic links with human diseases, etc.
In the year 2003, the Bioinformatics Facility was created at ACBR. The facility is now being funded and supported by the Department of Biotechnology (DBT), Govt. of India, since 2006.
Source
DBT-funded Bioinformatics Facility At ACBR (Dr. B.R. Ambedkar Center for Biomedical Research) Generates Drug Targets. DBT-funded bioinformatics facility (BIF) generates various potential drug targets.
