Jubilant Biosys MSc Biology, Biotech, Life Sciences, Genetics, Mol Bio RA Job – Apply Online
Jubilant Biosys MSc Biology, Biotech, Life Sciences, Genetics, Mol Bio RA Job – Apply Online. Master’s in Biology/Biotechnology/Molecular Biology/Genetics/Any life sciences stream candidates can apply for this job at Jubilant Biosys. Jubilant Biosys, Bangalore is hiring for Research Associate in Discovery Biology department – APPLY NOW
Role: Research Associate I – Discovery Biology
Location: Bangalore, Karnataka
Company: Jubilant Biosys Limited
Function: Research & Development
Roles & Responsibilities :
- Cell based assay development (optimization, validation and compound screening) under the Group leaders’ guidance.
- Enzyme based assay development (optimization, validation and compound screening)
- Invitro assay development, validation and optimization of cell based assay and enzyme based assay for various targets in the respective therapeutic areas such as CNS/
- Metabolic disorder/ Autoimmune/Inflammatory diseases/ Pain/Oncology in Drug Discovery field.
- Working extensively in the area functional cell based assays, validated the same to determine the activity of new chemical entities (NCEs).
- Responsible for writing of Protocols, uploading of the data, Lab note book record keeping. SOP writing.
- Analysis of experimental data using Graph pad PRISM (statistical Analysis Software) for IC50 and graphs.
- Designing experiments, execution, calculations, data analysis, graphical representations, report results to project teams.
- Follow the guidelines followed in the lab towards different safety aspects and help the lab head in designing the new guidelines.
- Follow ethical guidelines towards assay validation, data analysis and maintenance.
- Working in a team environment in order to deliver at a faster pace.
- Working as team player.
- Should exhibit zeal to learn new skills in respective research area.
Qualification: Master’s in Biology/Biotechnology/Molecular Biology/Genetics/Any life sciences stream.
Experience: 2 to 8 yrs
Desired Experience Required:
- Experience in a drug discovery industry/ CRO in invitro Research.
- Working experience of Tissue culture and cell culture Techniques
- Hands on experience in designing and execution of in vitro assays in CNS / Metabolic disorder/ Autoimmune/ Inflammatory diseases/ Pain/Oncology therapeutic area in Drug Discovery field.
- Skilled in handling mammalian cell lines.
- Expertise in western blotting, ELISA.
Below are some interview questions and answers related to the Research Associate I – Discovery Biology role at Jubilant Biosys Limited :
- Question: Can you explain your experience in cell-based assay development and validation? Answer: Sure! In my previous role, I was responsible for developing and optimizing cell-based assays under the guidance of Group leaders. I have experience in designing and executing assays for various therapeutic areas, including CNS, Metabolic disorders, Autoimmune, Inflammatory diseases, Pain, and Oncology. I have worked with mammalian cell lines and validated the assays to determine the activity of new chemical entities (NCEs).
- Question: How would you go about optimizing an enzyme-based assay for compound screening? Answer: To optimize an enzyme-based assay, I would start by determining the optimal enzyme concentration, substrate concentration, and reaction time. I would perform a series of experiments with different conditions and assess the assay’s sensitivity, specificity, and reproducibility. By systematically varying the assay parameters, I can identify the best conditions for accurate compound screening.
- Question: How do you handle data analysis for your assays? Answer: I typically analyze experimental data using statistical analysis software like GraphPad PRISM. For enzyme-based assays, I calculate the IC50 values and generate dose-response curves. In the case of cell-based assays, I analyze the effects of the compounds on cell viability or activity. I also use graphical representations to present the data effectively and make it understandable for the project teams.
- Question: Can you describe your experience in tissue culture and cell culture techniques? Answer: I have hands-on experience in tissue culture and cell culture techniques. I have worked extensively with various mammalian cell lines, maintaining their cultures, and ensuring their proper growth and health. Additionally, I have experience in setting up and performing different assays using these cell lines.
- Question: How do you ensure compliance with safety and ethical guidelines in the lab? Answer: I understand the importance of safety and ethics in the lab environment. To ensure compliance, I strictly follow the established protocols and standard operating procedures (SOPs) in the lab. I maintain detailed records in the lab notebook and follow all necessary guidelines when conducting experiments. Additionally, I actively communicate with the lab head and team members to implement any new safety guidelines or ethical considerations.
- Question: How do you manage your work in a team environment to deliver results efficiently? Answer: In a team environment, effective communication and collaboration are crucial. I ensure open communication with my team members, where we discuss project progress, share ideas, and resolve any challenges together. I believe in setting clear goals and deadlines, which helps us stay focused and work efficiently. I’m always willing to help others, share my knowledge, and learn from my teammates to contribute effectively to the team’s success.
Good luck with your interview!
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