Top 30 Biotech Startups Launched in 2019
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Top 30 Biotech Startups Launched in 2019Biotechnology Companies.

The term “Biotechnology” was coined by Karl Ereky to describe the combination of biology and technology. Ereky’s vision has been perceived by many companies as well as research institutions that are creating biotechnology products now and then.

Biotechnology has revolutionized different fields in biological sciences whether it is pharmaceutical, agriculture, health and food. Biotech is a very promising field with new inventions taking place every minute all around the world, attracting many young minds to build their career in this field as well as earn bread and butter.

How do these Biotech companies work?

The biotech company is a company that uses live organisms such as bacteria or their products, such as enzymes, to create drugs, but not limited to. Mostly the profit in biotech is in pharmaceuticals, medical devices, and diagnostics but many advances have also being made to develop, biofuels, biomaterials, resilient crops, and pollution controls. Roche, founded in the year 1896, in Switzerland is the largest biotech company in the world, with 17 biopharmaceuticals on the market.

Every year, new startups in biotech/biotechnology come up. Biotech startups are a high-risk venture and are different from a typical

tech Startup. The typical tech startup can launch a product within months, a biotech company often requires many years of thorough research and cash-burning before launching its first product in the market. The new startups include pharmaceutical companies, equipment firms provide servicing in research labs and scientists. These companies aim to provide knowledge, develop new technology and products.

This article will provide some insight into the top 30 Biotech startups which was launched in the past 12 months.

  1. Name of Startup: Arranta Bio
  • Categories: Biotechnology
  • Headquarters Location: Watertown, Massachusetts, United States
  • Website: http://arrantabio.com/

About Arranta Bio: Arranta Bio provides contract development and manufacturing services to pioneering innovators working on new therapies targeting diseases linked to the human microbiome. Arranta Bio is delivering on its vision to build the best-in-class microbiome contract development and manufacturing organization (CDMO) through its merger with a 10-year veteran CDMO, Captozyme, and the establishment of a commercial-ready manufacturing facility.

2. Name of Startup: Genesis Therapeutics

About Genesis Therapeutics: Their academia-leading research was the initial component of our expanding portfolio of AI technologies. This biotech startup is combining novel deep neural networks, biophysical simulation, and massively scalable computing infrastructure to achieve industry-leading performance in the molecular generation and property prediction.

3. Name of Startup: Thrive Earlier Detection

  • Categories: Biotechnology, Health Care, Medical
  • Headquarters Location: Cambridge, Massachusetts, United States
  • Website: https://thrivedetect.com/

About Thrive Earlier Detection: They envision a future in which blood was drawn at an annual physical that is used to find early-stage cancer. When found early, cancer is often effectively treated or even cured. Their goal is to integrate early cancer screening into routine medical care, helping to provide navigation for the care process. The few cancer screens available today, including mammograms and colonoscopies, each look for a single type of cancer. To work alongside these tests, they have built a test designed to find multiple cancer types from a single blood draw — including many cancers that lack effective screening tools such as ovarian, pancreatic, liver cancers and others.

4. Name of Startup: Civetta Therapeutics

About Civetta Therapeutics: Civetta Therapeutics was founded to advance new medicines through small molecule targeting of beta-propeller domains with the goal of developing important therapeutics for cancers and other diseases. By integrating a broad range of expertise in drugging the propeller domains spanning from biochemistry to biology to medicinal chemistry, this biotech startup company’s vision is to build a portfolio of therapeutics. These efforts will support the creation of near term therapeutics and longer-term value in becoming a leader in this space.

5. Name of Startup: Arvelle Therapeutics

About Arvelle Therapeutics: They bring innovative treatments to patients suffering from CNS disorders. Arvelle Therapeutics has licensed exclusive rights to develop and commercialize cenobamate in Europe from SK Biopharmaceuticals.

6. Name of Startup: HiberCell

About HiberCell: Despite significant advances in the treatment of primary tumors, metastatic cancer remains a leading cause of solid cancer mortality. HiberCell seeks to change that. This biotech startup is developing the first-in-class therapeutics that target dormant disseminated tumor cells (DTCs) from solid and liquid cancers. Their ultimate goal is to prevent or delay the recurrence of cancer. HiberCell is developing Novel Therapeutics to Prevent Relapse and Metastasis.

7. Name of Startup: Pyxis Oncology

  • Categories: Biotechnology, Health Care, Pharmaceutical
  • Headquarters Location: Boston, Massachusetts, United States
  • Website: https://www.pyxisoncology.com/

About Pyxis Oncology: Pyxis Oncology is developing antibody therapeutics to promote the body’s immune response to cancer, based on new insights into the tumor microenvironment. The tumor microenvironment represents a unique biological setting, different in many important ways from other sites of immune activity throughout the body.  Pyxis Oncology has unlocked many new avenues to restore the potency of dysfunctional immune cells through a deep understanding of the role of the tumor microenvironment in immune cell trafficking and activity. Pyxis is developing a diverse pipeline of new antibodies to enhance the immune response against cancer, even in tumor types that historically have not responded well to cancer immunotherapies.

8. Name of Startup: Kira Biotech

About Kira Biotech: Kira Biotech is an emerging Australian biotechnology company developing novel immunomodulatory compounds for the treatment of immune system disorders.  Its lead candidate, KB312, is a first-in-class, selective, immune-cell depleting monoclonal antibody that targets activated immune cells and aims to restore homeostasis through induction of immune tolerance.  Kira Biotech has attracted venture capital funding and is progressing KB312 through preclinical development and phase 1 clinical trials with a team of drug development experts led by well-known US-based rheumatologist and immunologist, Dr. Dan Baker.

9. Name of Startup: Chinook Therapeutics

About Chinook Therapeutics: Drug development in kidney diseases is experiencing a resurgence due to a greater understanding of disease biology, utilization of novel translational platforms and patient stratification tools, and the emergence of accelerated regulatory pathways based on surrogate endpoints.

10. Name of Startup: Cell Vault

  • Categories: Biotechnology
  • Headquarters Location: Daytona Beach, Florida, United States
  • Website: https://cellvault.com/

About Cell Vault: Cell Vault is one of the Biotech Startups launched in 2019. It has launched the world’s first t-cell bank to give individuals an opportunity to jumpstart their fight against cancer. Just as women freeze their fertile eggs, Cell Vault allows you to preserve your disease-fighting t-cells in case they can be used in future medical treatment.

11. Name of Startup: Rosa Biotech

  • Categories: Biotechnology, Machine Learning, Manufacturing
  • Headquarters Location: Bristol, Bristol, City of, United Kingdom
  • Website: https://www.rosabio.tech/

About Rosa Biotech: Rosa Biotech is redefining biosensing. They are enabling previously intractable challenges in early disease diagnosis and industrial biotechnology to be addressed accurately and at scale. They are based at the Unit DX biosciences hub in the heart of Bristol. Located near Bristol Temple Meads station, the hub is home to over 20 science-driven companies, startup and spinout companies, investors and support services, and provides a melting pot of academic researchers.

12. Name of Startup: Araris Biotech

About Araris Biotech: Araris Biotech AG is a spin-off company from the Paul Scherrer Institute (PSI) and ETH Zurich pioneering a novel antibody-drug conjugate (ADC)-linker technology. Their linker platform enables the attachment of any payload to ‘off the shelf’ antibodies without the need for prior antibody engineering. ADCs are powerful biopharmaceuticals, delivering highly potent drugs very specifically to the desired tissue. ADCs consist of highly potent cytotoxic agents conjugated to antibodies through a specific linker. This molecular format enables the highly-selective delivery of any payload to the diseased tissue, while healthy parts of the human body are spared.

13. Name of Startup: Lavie bio

  • Categories: Agriculture, Biotechnology
  • Headquarters Location: Rehovot, HaMerkaz, Israel
  • Website: lavie-bio.com

About Lavie bio: As a biotech startup their Mission is to improve food quality, agricultural sustainability, and productivity through the introduction of microbiome-based ag-biological products. Better food for consumers with improved quality and health attributes. Better agriculture for a sustainable environment. Nature is the ultimate resource – they partner with the untapped potential of the microbiome.

14. Name of Startup: AHEAD Medicine

  • Categories: Analytics, Artificial Intelligence, Biotechnology, Health Care
  • Headquarters Location: Berkeley, California, United States
  • Website: http://aheadmedicine.com/

About AHEAD Medicine: AHEAD medicine focuses on the development and application of AI-enabled diagnostic and disease assessment tools for blood cancer treatment. Leukemia detection models are developed that allow physicians to identify abnormal cases promptly and can prevent delays in clinical decisions. To enable AI aided clinical decision making in the blood cancer treatment for every physician and help them tackle challenges in blood cancer management with better treatment strategies is our vision. Biotech Startup launched in 2019.

15. Name of Startup: PolyProx

  • Categories: Biotechnology, Health Care, Therapeutics
  • Headquarters Location: Cambridge, Cambridgeshire, United Kingdom
  • Website: https://www.polyprox.com/

About PolyProx: PolyProx Therapeutics is a Biotech Startup launched in 2019 – focused on the discovery and development of a new class of drugs, Polyproxin molecules, to treat cancer and neurodegenerative diseases. Polyproxin molecules are biopharmaceuticals that selectively target disease-causing proteins and use natural cellular pathways to degrade or remove these proteins. For use in the treatment of cancers, targeting aberrant proteins that have previously proven difficult to target using conventional drug classes, such as small molecules or monoclonal antibodies, our initial focus is on developing Polyproxin drug candidates for these.

16. Name of Startup: Nimble Therapeutics

About Nimble Therapeutics: Nimble Therapeutics supports all phases of preclinical development to accelerate your path to the clinic. Nimble is using its unique maskless chemical synthesis platform to synthesize and systematically discover novel medicines in a variety of therapeutic areas. Nimble harnesses the power of photolithography and an extensive library of photoprotected amino acids to enable the design, synthesis, and screening of millions of diverse macrocycles at unprecedented speed. Nimble’s core capabilities have been applied in various studies and have helped unlock new learnings and discoveries.

17. Name of Startup: CysBio

  • Categories: Biotechnology
  • Headquarters Location: Kongens Lyngby, Hovedstaden, Denmark
  • Website: https://cysbio.com/

About CysBio: Cysbio uses advanced metabolic engineering and synthetic biology approaches to construct bacterial cell factories for transforming the production of biochemicals from renewable feedstocks. Their proprietary cell factories produce commodity chemicals for existing markets, and Cysbio technologies enable the production of entirely new chemicals with novel properties. Cysbio is a spin-out from the Novo Nordisk Foundation Center for Biosustainability at the Technical University of Denmark.

18. Name of Startup: Qlaris Bio

  • Categories: Biotechnology
  • Headquarters Location: Cambridge, Massachusetts, United States
  • Website: https://qlaris.bio/

About Qlaris Bio: Qlaris Bio was founded with a singular focus: to develop novel, innovative therapies for serious and debilitating ophthalmic diseases. Qlaris Bio is a spinout company of Qrativ, a biotechnology incubator formed as a joint venture between Mayo Clinic and inference, a pharmaceutical-focused artificial intelligence company.  Qlaris Bio’s lead program is QLS-101, a novel compound invented at Mayo Clinic and the University of Minnesota. QLS-101, with its unique and first-in-class mechanism of action, may potentially serve as an efficacious treatment for high unmet need conditions related to disturbances in intraocular pressure, including a sight-threatening and progressive Pediatric Rare Disease for which effective therapies remain elusive and limited.

19. Name of Startup: CellmAbs

About CellmAbs: CellmAbs is a biotech company focused on the discovery and development of cutting edge oncology products, aiming to deliver the most effective and safe therapeutic and diagnostic solutions to treat cancer patients. Their ultimate goal is to cure cancer and they work passionately every day to achieve it. Their team is comprised of renowned scientists and international experts in the field of glycoimmunology and oncology. They also maintain several partnerships and collaborations with national and international research centers and oncology clinical institutes.

20. Name of Startup: Pregenerate

About Pregenerate: At Pregenerate, they use scaleable organ-on-a-chip models to replace animal testing in pharmaceutical research for arthritis treatments. This enables pharmaceutical companies to save billions of dollars and improve the success rates of their drugs to market, in part because of using human cells in their company’s model.

21. Name of Startup: TissueLabs

  • Categories: 3D Technology, Biotechnology, Life Science, Medical, Therapeutics
  • Headquarters Location: Sao Paulo, Brazil
  • Website: https://www.tissuelabs.com/

About TissueLabs: They are building a new platform to create organs and tissues in the lab. By combining tissue-specific extracellular matrix proteins as self-assembling hydrogels, we offer the most advanced microenvironment for cell and tissue culture. Their products are created to allow you to perform state of the art research, from drug discovery to organ fabrication.

22. Name of Startup: Nagi Bioscience

  • Categories: Biotechnology
  • Headquarters Location: Lausanne, Vaud, Switzerland
  • Website: http://nagibio.ch/

About Nagi Bioscience: Meet the first Organism-on-Chip Technology. The first Organism-on-Chip technology, proudly introduced by Nagi Bioscience – Biotech Startups 2019, combines the use of a simple yet complete organism for in vivo testing – the tiny worm “Caenorhabditis Elegans” – with the first technological platform for its fully automated in vitro handling, analysis and culture. Unprecedented possibilities are now open, for a wide range of applications, including toxicity, anthelmintics, and drug discovery.

23. Name of Startup: JOGO Health

  • Categories: Biotechnology, Fitness, Health Care, Pharmaceutical
  • Headquarters Location: Bridgewater, New Jersey, United States
  • Website: https://www.jogohealth.com/

About JOGO Health: JOGO  helps healthy brain cells rewire to work with muscles that have become inactive due to stroke and other neuromuscular conditions. A prescription digital therapeutic product, JOGO is composed of a patent-protected Mobile App, and wearable wireless s/EMG  sensors, that provide games and treatment protocols that can be adapted for muscle relaxation, all leveraging neural plasticity, movement coordination, and neuro-muscular re-education.

24. Name of Startup: Transcenta

About Transcenta: Transcenta is a global biotherapeutics company that fully integrates antibody-based biotherapeutics discovery, R&D, regulatory affairs and manufacturing. At Transcenta, they focus on helping patients around the world by employing cutting-edge technology to discover and deliver high-quality innovative biologics at affordable prices.

25. Name of Startup: FUMI Ingredients

About FUMI Ingredients: They produce animal-free food ingredients from micro-organisms. They believe that microorganisms are an untapped source of high-value ingredients, which can be used in a broad range of healthy food products. FUMI Ingredients uses natural micro-organisms such as baker’s and brewer’s yeast and micro-algae. They have developed a mild and scalable process, which is able to recover unique compounds from these untapped resources.

26. Name of Startup: Mantle Biotech

  • Categories: Biotechnology, Health Care, Health Diagnostics, Medical, Wellness
  • Headquarters Location: Cambridge, Massachusetts, United States
  • Website: http://mantlebiotech.com

About Mantle Biotech: They engineer binding proteins that can accurately detect disease biomarkers in patient samples, using directed evolution to modify heat-stable proteins produced by microbes found living in hot springs. These versatile reagents can be adapted to a range of diseases and test formats, enabling our team to address pain points throughout the broader diagnostic industry.

27. Name of Startup: Epigene Labs

About Epigene Labs: Over the past couple of decades, the exponential progress of sequencing technologies has allowed an increasing number of cancer patients to benefit from precision oncology. However, the aggregation, analysis, and visualization of the massive amounts of genomic data remain a major challenge for precision oncology expansion. The Epigene Labs technology platform – Biotech Startup launched in 2019 – enables cancer drug hunters to seamlessly leverage advanced artificial intelligence in transforming genomic data into actionable insights for designing precision oncology approaches. With R&D in Paris and business development in Boston, Epigene Labs operates in the setting of value-based partnerships with world-leading cancer centers and high-profile biotechs.

28. Name of Startup: Percayai

  • Categories: Artificial Intelligence, Biotechnology, Pharmaceutical
  • Headquarters Location: St Louis, Missouri, United States
  • Website: https://www.percayai.com/

About Percayai: They are an interdisciplinary team of computer scientists, computational biologists and chemists, and life science executives devoted to understanding the complexities of human biology. PercayAI – a Biotech Startup – is reimagining the drug discovery process by providing truly innovative augmented intelligence software. Percaya is a Bahasa Indonesian word meaning “believe” or “trust,” while AI refers to our “Augmented Intelligence” software products.

29. Name of Startup: Ventnostics

  • Categories: Biotechnology, Chemical Engineering, Health Diagnostics, Life Science, Mechanical Engineering, Medical Device
  • Headquarters Location: San Francisco, California, United States.
  • Website: https://www.ventnostics.com/

About Ventnostics: Ventnostics is a biomedical engineering biotechnology company developing over-the-counter, affordable, and easy-to-use screening tests for mosquito-borne diseases. Ventnostics’ mission is to simplify and miniaturize complex medical diagnostic tests so that they can reach millions of people around the world.

30. Name of Startup: RNAissance

About RNAissance: RNAissance Ag is an ag biotechnology company focused on delivering RNA-based insecticides for crop protection. RNA-based insecticides are environmentally friendly, and designed to be specific to particular target insects. They have a novel technology with a new mode of action. They will focus on developing spray-on RNA insecticides.

Those were the top 30 Biotech Startups launched in 2019. So, whether it’s about advancement in combinatorial genomics or gene-editing technology, scientists have joined hands to change the future biotech and healthcare based industries. Problem-solving approach, timing, teamwork, progress are important to make a successful company and to succeed as an entrepreneur. How exciting it is to see many biotech startups launching each year for the betterment of human life using the combination of technology and biological sciences.

This article provides brief information about the Biotech companies which are doing extraordinary work in several fields ranging from therapeutic developments for various diseases as well as health data management. For more details company web sites can be referred.

Author: Prathibha HC

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1 COMMENT

  1. Useful information given by biotecnika,but one request is to provide relevant information among India also. Thank you

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