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First Incompatible Kidney Transplant Conducted On A Nine-Year Child Successfully

Girish Thorat was detected with nephrotic syndrome at the age of six and after that Girish was put on medicines and underwent biopsy twice, but it took three years for him to be put on peritoneal dialysis-a treatment for severe chronic kidney disease.
At that time Girish’s grandmother decided to give her kidney to the child. The only hitch was that their blood groups were incompatible (ABO mismatch).

However, in a first of its kind paediatric kidney transplant, Aditya Birla hospital doctors successfully treated the nine-year-old, gifting him a dialysis-free life.

The surgery was performed on April 4. Girish was discharged from the hospital on Tuesday. His maternal grandmother donated the kidney. The hospital claimed it was the first incompatible blood group paediatric kidney transplant without plasma exchange in the country.

Addressing a news conference nephrologist Tarun Jeloka said the team of doctors also comprised urologists Amol Patil, Anand Dharashkar and Naresh Rao, and anaesthetists Paramjeet Garcha and Ashish Pathak.

Jeloka said, “Earlier, blood group compatibility between the donor and the recipient was needed for a successful kidney transplant. Nowadays, kidney transplants in incompatible blood group are also successfully conducted

in adults. Twenty such successful transplants have been conducted at ABMH (Aditya Birla Memorial Hospital). Mostly plasma exchange technique is used in these cases. This is the first time incompatible paediatric kidney transplant,too without plasma exchange, was conducted in a child.”

Girish is the son of Dr Jaywant Thorat, a medical officer at the Satara Zilla Parishad-run primary health centre at Yevati village. His family lives in his ancestral village Ond, around 16km from Karad. His mother, Sujata, is a BAMS doctor.

Jaywant said the family was exploring kidney transplant for him. “During one such discussion with the family members, his 60-year-old maternal grandmother, Shantabai Desai, expressed the desire to donate her kidney. I came to ABMH and later tests were conducted on her and Girish in January,” he said.

Rekha Dubey, CEO, Aditya Birla Memorial Hospital, said, “this is the city’s first incompatible blood group (ABO mismatch) pediatric kidney transplant, that too without plasma exchange, which is very rare even in the country”.

Peace-lover, creative, smart and intelligent. Prapti is a foodie, music buff and a travelholic. After leaving a top-notch full time corporate job, she now works as an Online Editor for Biotecnika. Keen on making a mark in the scientific publishing industry, she strives to find a work-life balance. Follow her for more updates!