NIBMG Biological Sciences Project Job, BSc & MSc Candidates Apply Online

NIBMG Biological Sciences Project Job, BSc & MSc Candidates Apply Online

NIBMG Biological Sciences Project Job, BSc & MSc Candidates Apply Online. MSc & BSc Biological Sciences Project Assistant jobs. Interested and eligible applicants can check out all of the details below

Possible Interview Questions for the posts of JRF and Lab Assistant vacancies at NIBMG are posted below

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NATIONAL INSTITUTE OF BIOMEDICAL GENOMICS
(An Autonomous Institution of the Government of India)
P.O.: N.S.S., Kalyani 741251, West Bengal, INDIA
www.nibmg.ac.in

Advertisement No. NIBMG/ADMIN/ESTB/2023-24/71

Position available

Project name: Antiviral Epigenetics

Brief Description: Within the scope of this project, the differential histone modifications in enhancer/promoter region of Interferon Stimulating Genes (ISGs) in virus infected mammalian cells has been examined. Moreover, the regulation of histone modifiers (HAT, HDAC) and different chromatin readers during antiviral immune response will also be investigated. The project has been initiated with SARS-CoV-2 viral proteins. In the current year of the project, live SARS-CoV-2 virus-infected samples will be used to validate the previously obtained results about epigenetic modification in anti-viral immune response.

Name of the Post: Project Assistant

No. of Posts: 01

Consolidated and fixed monthly emolument – Rs 20,000/-

How to Apply

This position is contractual. The appointment will be given for one year, which is NOT extendable. Interested candidates are requested to apply online at https://apply.nibmg.ac.in (no other form of application will be accepted). The last date for application is 26th June 2023 (till 5 PM). Please visit www.nibmg.ac.in for further information. Only the shortlisted candidates will be called for an interview at NIBMG. The tentative interview date for short-listed candidates will be 3rd July 2023 from 10.30 am.

NIBMG reserves the right to raise the minimum eligibility standards/criteria and/or to conduct a screening test, to restrict the number of candidates to be called for Personal Interviews if so required. The decision of NIBMG in all matters relating to eligibility, acceptance or rejection of the application, mode of selection, and conduct of interviews will be final and binding on the applicants. In exceptionally meritorious cases, the eligibility requirements may be relaxed by the competent authority.

Essential Qualifications – Master’s degree in any Biological Science discipline OR B.Sc. in any Biological Science discipline with experience in a related field.

Desirable Qualifications –

1. Experience in genetic and genomic data analysis.
2. Hands-on working experience in molecular biology techniques (e.g., PCR, cloning, RT-PCR) and data analysis.

Nature of Duty –

1. Mammalian Cell culture and virus culture using BSL-3 facility.
2. Basic molecular biology work.

APPLY ONLINE

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Possible Interview Questions for the posts of Project Assistant vacancy at NIBMG:

1. Can you describe your experience and knowledge in genetic and genomic data analysis? Provide examples of projects or research where you have applied these skills. Answer: I have experience in genetic and genomic data analysis through my Master’s degree program. In my research project, I analyzed RNA-Seq data to identify differentially expressed genes in response to a specific treatment. I performed data preprocessing, quality control, and differential gene expression analysis using bioinformatics tools such as R and Python. Additionally, I have worked with genomic data analysis pipelines and have a good understanding of variant calling and annotation.
2. Have you worked with mammalian cell culture and virus culture using BSL-3 facilities? Can you elaborate on your experience and any specific protocols or techniques you have utilized? Answer: Yes, I have hands-on experience in mammalian cell culture and virus culture using BSL-3 facilities. In a previous project, I cultured various mammalian cell lines and maintained their viability and sterility. I followed strict protocols for aseptic techniques, media preparation, and passaging cells. Additionally, I have experience in virus culture, including the handling of live viruses, implementing safety measures, and performing viral titer assays.
3. Have you utilized molecular biology techniques such as PCR, cloning, and RT-PCR in your research work? Can you provide examples of experiments or assays where you have applied these techniques? Answer: I am proficient in molecular biology techniques such as PCR, cloning, and RT-PCR. In one of my research projects, I designed and optimized PCR primers for amplifying specific gene targets. I performed cloning experiments to transfer the amplified DNA fragments into expression vectors for further analysis. I have also conducted RT-PCR experiments to measure gene expression levels in different experimental conditions or disease states.
4. Can you discuss your familiarity with histone modifications and their role in gene regulation? How do you envision studying differential histone modifications in the enhancer/promoter regions of Interferon Stimulating Genes (ISGs) during antiviral immune response? Answer: Histone modifications play a crucial role in gene regulation by influencing chromatin structure and accessibility. Specifically, modifications like acetylation and methylation of histone proteins can affect gene expression. In the context of antiviral immune response, studying the differential histone modifications in the enhancer/promoter regions of ISGs can provide insights into the epigenetic regulation of immune signaling pathways. This can help us understand the dynamics of gene expression and the underlying mechanisms of antiviral immune response.
5. Have you conducted data analysis for epigenetic studies before? Can you discuss the approaches or tools you have used to analyze histone modification data? Answer: Yes, I have experience in data analysis for epigenetic studies. For histone modification data analysis, I have used various bioinformatics tools and software packages such as MACS, HOMER, and BEDTools. These tools allow for peak calling, differential peak analysis, and visualization of histone modification patterns. Additionally, I have employed statistical methods and pathway enrichment analysis to identify functional implications of differentially modified regions. Overall, my experience in epigenetic data analysis enables me to extract meaningful insights from histone modification data.

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