Syngene Immunology & Cell

Syngene Immunology & Cell Biology Research Investigator Job – Apply Online

Syngene Immunology & Cell Biology Research Investigator Job – Apply Online. PhD Immunology and Cell Biology Clinical Flow Cytometry – Research Investigator job at Syngene – APPLY NOW

Designation: Research Investigator- Translational Medicine-Clinical Flow Cytometry (7-I)

Job Location: Bangalore

Job ID: 54722

Department: TM-TSDX- Clinical Flow Cytometry

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose:

This position is within the clinical flow cytometry team of Translational Medicine (TM) at BBRC, Syngene. You will play a key role in drug discovery and clinical development by providing technical expertise for design, execution and results interpretation of high order multicolor flow cytometry assays. Work

in a collaborative manner with internal and external stakeholders to enable program transition to the next stage. Execute and oversee assay development, validation, instrument calibration/quality assurance and maintenance of the flow cytometers.  Support clinical sample analysis. Develop new capabilities in high order flow cytometry to support the development of biomarker assays as per program needs. Day to day oversight and management of team of scientists.

Key Responsibilities:  

  • Collaborate with program leads to understand requirements and support project needs
  • Provide technical expertise for design and execution of flow cytometry assays at the lab bench
  • Perform assay development and validation
  • Oversee clinical sample analysis and data interpretation
  • Deliver on projects within timelines.
  • Oversee maintenance and calibration of flow cytometers
  • Lead a team of 1-2 Scientists and oversee their day to day activities
  • Establish advanced flow cytometry capabilities in the team
  • Lead exploratory research projects

Educational Qualification:  

PhD in Immunology/Oncology/ Heme malignancies/Cell biology or related disciplines with 1-5 years relevant experience of working on high order multi-color flow cytometry assays in industry/academic research.

Technical/functional Skills: (Maximum 4-6 Points)

  • Background and expertise in Immunology/Cell Biology/Molecular Biology/Biochemistry/Oncology/Heme malignancies
  • Experienced in design, execution and data interpretation of multicolor flow cytometry assays (required)
  • Experience working on diverse flow cytometer instruments. Demonstrated capability of working on research projects and delivering under tight timelines
  • Experience with third party flow cytometry data analysis softwares (eg: Flowjo, FCS express, etc)
  • Experience working in drug discovery will be a plus
  • Excellent publication record and demonstrated ability for independent research
  • Having worked with human clinical samples is desired.
  • Statistical skills and understanding of experimental design
  • Familiarity with unsupervised flow cytometry data analysis tools will be considered a plus. Usage of scientific softwares like graphpad prism or equivalent
  • Research oriented mindset.

Experience: 1-5 years of prior experience in industry or academic institutes with exposure to flow cytometry technology platform

Behavioural Skills:

  • Excellent communication and presentation skills
  • Ability to work collaboratively as part of a multi-disciplinary team
  • Ability to adapt to dynamic work environment
  • Strong analytical and troubleshooting skills
  • Good documentation skill set
  • Team player and able to adapt to a fast-changing work environment

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.

Send your CV to:

[email protected]

Possible Interview Questions and Answers for the Research Investigator- Translational Medicine-Clinical Flow Cytometry Position:

  1. Question: Can you describe your experience in designing and executing multicolor flow cytometry assays in an industry or academic research setting? Answer: Certainly, during my PhD in Immunology, I focused on developing and executing high order multi-color flow cytometry assays for studying [mention specific research focus]. I have successfully contributed to multiple projects involving diverse flow cytometer instruments, managing tight timelines, and interpreting complex data.
  2. Question: How do you ensure the accuracy and reliability of flow cytometry data interpretation? Can you share an example of a challenging data interpretation situation you faced and how you resolved it? Answer: Data accuracy is crucial in flow cytometry. I ensure this by meticulous instrument calibration, proper gating strategies, and rigorous quality control. Once, while analyzing a complex flow cytometry dataset, I encountered overlapping populations. I addressed it by optimizing gating parameters and seeking input from colleagues, resulting in accurate interpretation.
  3. Question: Could you explain your experience in leading a team and managing day-to-day activities of scientists? How do you ensure efficient collaboration and communication within your team? Answer: I have led a team of scientists during my previous role, overseeing their work, ensuring alignment with project goals, and facilitating effective communication. Regular team meetings, clear project expectations, and a supportive environment enabled seamless collaboration and streamlined progress.
  4. Question: How would you approach establishing advanced flow cytometry capabilities within the team to support the development of biomarker assays? Answer: To establish advanced capabilities, I would begin by assessing the team’s existing skills and resources. Then, I would identify training needs, explore new techniques, and implement best practices. Collaborating with experts and conducting thorough validations would ensure a robust flow cytometry platform for biomarker assay development.
  5. Question: Flow cytometry data analysis is a crucial aspect. Can you elaborate on your experience with third-party flow cytometry data analysis software and its role in your research projects? Answer: I am proficient in using software like Flowjo and FCS Express for in-depth flow cytometry data analysis. For instance, in a project investigating [mention project focus], these tools helped me analyze complex data, identify cell subsets, and visualize results effectively, contributing to the project’s success.

These questions provide insights into the candidate’s technical skills, leadership abilities, problem-solving approach, and experience with flow cytometry techniques and data analysis tools. The answers demonstrate their practical knowledge, experience, and adaptability to various challenges in the role.

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