Sound For Drug Delivery
A technique conventionally adapted from telecommunications promises an effective cancer treatment. Melbourne researchers have discovered that drugs can be delivered into individual cells by using soundwaves.
Dr. Shwathy Ramesan from RMIT and a team of researchers adapted a technique used in the telecommunications industry for decades. The new technique-Sound For Drug Delivery- aids in silencing genes responsible for diseases, including cancer, by switching them on or off.
Dr. Shwathy Ramesan said that recent success in gene therapies has armed the medical professionals with the exciting possibility of isolating a patient’s target cells and then re-engineering them in the lab & re-infusing them back into the same body. She highlighted that this new technique brings reality significantly closer.
Cells in our body actively reject most delivered drugs. The key challenge faced by the researchers in the Sound For Drug Delivery project is to get the engineered cells back is overcoming the body’s innate resistance to foreign entities.
Shwathy and her team have developed a microchip that produces precise soundwaves. The soundwaves produced by the chip are inaudible to the human ear. These soundwaves can be used to control the exact manipulation of drug uptake at the sub-cellular levels.
This technique -Sound For Drug Delivery– not only increases the drug delivery percentage inside the cells but also reduces the death rates substantially. These features make it an attractive drug delivery technique.
Dr. Shwathy and the team have successfully demonstrated the technique in preliminary lab-based experiments. The results are published in the journal Nanoscale.