Research Job at INST | Life Sciences | Apply Now
The Institute of Nano Science and Technology (INST), Mohali, is inviting applications for a high-impact Research Job funded by the Indian Council of Medical Research (ICMR). This project targets one of the most challenging hurdles in cancer treatment: chemoresistance in colon cancer. If you are a life sciences professional looking for a Life Sciences Job that merges nanotechnology with molecular oncology, this role under Dr. Sharmistha Sinha offers a prestigious platform for preclinical exploration.
About the Institute
INST is an autonomous institute of the Department of Science and Technology (DST), Government of India, located in the Knowledge City of Mohali, Punjab. The institute is dedicated to the study of Nanoscience and Nanotechnology, applying these fields to solve problems in agriculture, energy, and medicine. It provides a world-class environment for a Life Sciences Job, featuring high-end analytical suites and a vibrant community of scientists like Dr. Sharmistha Sinha (Scientist F).
Project Details
The project, titled “Preclinical Investigations on p53 Condensates as a Therapeutic Target for Overcoming Chemoresistance in Colon Cancer,” dives into the cutting-edge field of liquid-liquid phase separation (LLPS) in cancer biology.
- The Target: p53 is often called the “guardian of the genome,” but its aggregation or condensation can lead to a loss of function, driving cancer progression.
- The Problem: Chemoresistance in colon cancer remains a major cause of treatment failure; this research investigates how protein condensates contribute to that resistance.
- The Goal: Identifying p53 condensates as therapeutic targets to sensitize cancer cells to chemotherapy.
- Methodology: The work involves a sophisticated blend of molecular biology, biophysical characterization, and advanced mammalian cell culture.
Position Details & Eligibility
This Research Job is a temporary, contractual position that offers a gateway into the regular PhD program at INST for eligible candidates.
- Position Name: Project Technical Support-III (01 Post).
- Monthly Fellowship: ₹28,000 + 20% HRA (Total approx. ₹33,600).
- Essential Education (Option A): Three-year graduation in life/allied sciences plus 3 years of research experience.
- Essential Education (Option B): Two-year Post-graduation in Life and allied sciences.
- Desirable Experience: Candidates with national-level qualifications (CSIR/UGC-NET, GATE, or ICMR-JRF) are preferred.
- Technical Skills: Prior hands-on experience in mammalian cell culture, molecular biology, and biophysical techniques is highly valued.
- Age Limit: Maximum 35 years as of March 16, 2026 (relaxations apply for reserved categories).
- Duration: Initially for one year, extendable up to three years based on performance and funding.
Application Details
- Last date of receipt of application: 16.03.2026
- Application Mode: Email only.
- Requirement: Submit a combined PDF containing your CV and self-attested copies of all testimonials (age proof, degrees, mark sheets).
- Email Address: Send your application to [email protected].
- Interview Mode: Hybrid (Option for both Online and Offline interviews).
- No TA/DA: No travel allowance is provided for attending in-person interviews.
In summary, this Research Job at INST Mohali is a definitive opportunity for scientists eager to tackle the complexities of colon cancer. This Life Sciences Job doesn’t just offer a paycheck; it offers a chance to work on p53, one of the most studied proteins in human history, through the lens of modern nanomedicine. Because the deadline is so tight (March 16), ensure your CV highlights your specific experience with cell culture and molecular biology to stand out to Dr. Sinha’s team.
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