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Job Title: Structural Biologist – Drug Discovery
Company: Meril Life Sciences
Location: Vapi, Gujarat, India
Salary Range (Full-Time): ₹3 LPA – ₹6 LPA
Experience: Freshers Welcome (Internship will be provided before full-time role)
Key Responsibilities
- Perform structure-based design of small molecules and protein therapeutics
- Determine and analyze protein structures to support drug discovery programs
- Study protein–ligand interactions to guide medicinal chemistry and lead optimization
- Conduct molecular dynamics simulations and free energy calculations to assess binding stability
- Apply structural insights to support hit-to-lead and lead optimization strategies
- Collaborate with computational biology, medicinal chemistry, and biology teams
- Maintain proper documentation and ensure high-quality data analysis
- Apply machine learning tools for binding site prediction or compound prioritization (preferred)
Required Skills
- Strong understanding of structural biology techniques such as X-ray crystallography, Cryo-EM, or NMR
- Knowledge of macromolecular modeling and visualization tools such as Phenix, Coot, Chimera, and PyMOL
- Familiarity with protein–ligand docking, structure validation, and interaction analysis
- Exposure to molecular dynamics simulation tools like GROMACS, AMBER, NAMD, or CHARMM
- Basic understanding of structure-based drug design platforms such as Schrödinger or AutoDock
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Programming or scripting knowledge in Python, R, or Bash for data analysis (preferred)
Educational Qualification
PhD / MS / MTech in Structural Biology, Computational Biology, or a related field


















