
Syngene Careers hiring for Principal Scientist Job – Protein Purification | Life Science Jobs
Ready to step into a leadership-driven Principal Scientist Job at one of India’s most respected CROs? Syngene Careers invites accomplished PhD professionals to lead high-impact protein purification initiatives within Discovery Biology. This role is a rare opportunity for scientists seeking senior Life Science Jobs that blend hands-on expertise, team leadership, and innovation-driven research under global quality and safety standards.
- Job Title: Team Lead- Protein Purification
- Location: Bangalore
- Division: Discovery Services
- Department: Discovery Biology
About the Company:
Syngene (Syngene International Ltd.) is an innovation-led contract research, development, and manufacturing organization offering integrated scientific services from early discovery to commercial supply. Known for scientific excellence, integrity, and professionalism, Syngene Careers represent some of the most trusted Life Science Jobs in India’s biopharmaceutical ecosystem.
Job Overview:
This Principal Scientist Job within the Discovery Biology department focuses on leading protein purification activities, protocol optimization, quality analysis, and team mentorship. The role demands strong technical expertise, project ownership, cross-functional collaboration, and strict adherence to Syngene’s EHS, data integrity, and quality standards while managing multiple discovery-stage programs.
Key Responsibilities:
- Independently perform protein purification and quality checks using SDS-PAGE and SE-HPLC
- Optimize protein purification protocols using AKTA systems and batch methods
- Develop purification strategies involving affinity, ion exchange, and size exclusion chromatography
- Maintain detailed experimental records, reports, and scientific presentations
- Manage multiple discovery projects under strict timelines
- Support, troubleshoot, and mentor junior team members
- Ensure lab cleanliness, equipment maintenance, and safety compliance
- Drive EHSS culture, safety metrics, and quality adherence as a Syngene leader
Educational Requirements:
- PhD in Life Science, Biochemistry, or Biotechnology
- Hands-on industry experience in protein purification and discovery biology
8. Skills Required:
- Strong theoretical and practical expertise in protein purification techniques
- Hands-on experience with AKTA Pure, Prime Plus, Explorer, and Start systems
- Proficiency in buffer preparation, molarity calculations, and pH adjustments
- Experience with analytical techniques such as SE-HPLC and SDS-PAGE
- Leadership, team management, and matrix collaboration skills
- Excellent scientific documentation, communication, and presentation abilities
- Strong analytical mindset with multitasking and project management capability
If you are seeking a leadership-focused principal scientist job that offers scientific ownership, career growth, and exposure to world-class discovery programs, Syngene Careers provides a powerful platform to elevate your impact in the life sciences industry.

















