Syngene Hiring MSc Biochemistry for Senior Research Associate Position
Syngene Hiring MSc Biochemistry for Senior Research Associate Position. Interested Candidates can check out the details below and Apply Online
Job title: Senior Research Associate
Job Location: Bangalore, India
Job id: 54826
Job Category: Pharmacokinetics and Immunogenicity Assays
Job Type: Full Time
JOB DESCRIPTION
Job Purpose:
The position holder is responsible for performing bioanalysis which includes performing ligand binding assays related to Pharmacokinetics and Immunogenicity.
Key Responsibilities:
• Ensure activities conducted in the bioanalytical lab are in compliance with established SOPs, procedures, systems, regulatory guidance without deviating from established procedures.
• Regular interaction and participation with Study director, Quality Control (QC) and Quality Assurance (QA) during raw data and reports review, closure of observations and archival.
• Ensure to complete the assigned tasks in timely manner.
• Prepare reagents, buffers and maintain log book for assigned assays
• Interpret results – anticipate and understand the issues related to the assay.
• Participate in, and present data for discussions.
• Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety.
• Attend training on environment, health, and safety (EHS) measures imparted company
Technical/functional Skills:
• Should have a strong background in immunoassay and bioanalytical Pharmacokinetics and Immunogenicity Assays with a good understanding as per regulatory guidance/ industry practices/internal Standard Operating Protocols.
• Should have hands-on experience in Ligand Binding Assay (LBA) development, validation and Sample analysis. Knowledge of ELISA and MSD assays are highly desirable.
• Knowledge and experience with regulatory requirements e.g. Organization for Economic Co-operation and Development (OECD), GXP, 21 CFR Part 11, European Medicines Agency (EMA) and Food and Drug Administration (FDA) guidelines.
Behavioral Skills:
• Should be independent.
• Excellent communication skills – written and oral in English
• Should have good interpersonal skills
• Large degree of flexibility and ability to work under strong time pressure
Educational Qualification:
• Master’s degree in Biological Sciences (Preferably Biochemistry background) or a related field.
Experience:
• 3-6 years of total experience in Pharmacokinetics and Immunogenicity Assays
Syngene Hiring MSc Biochemistry for Senior Research Associate Position. Here are five Possible interview questions along with their potential answers :
Question 1: Can you describe your experience with ligand binding assays and their importance in pharmacokinetics and immunogenicity studies? Answer: Ligand binding assays (LBAs) play a crucial role in quantifying the interactions between target molecules and analytes. In pharmacokinetics, LBAs help us understand the concentration profiles of drugs in biological samples. Immunogenicity assays, on the other hand, are essential for evaluating the immune response generated against therapeutic molecules. My experience includes developing, validating, and analyzing LBAs to assess pharmacokinetics and immunogenicity. I have hands-on experience with techniques such as ELISA and MSD assays, which are commonly used in these studies.
Question 2: How do you ensure compliance with regulatory guidelines and established SOPs while conducting bioanalytical experiments? Answer : Ensuring compliance is a critical aspect of bioanalytical work. I meticulously follow established Standard Operating Procedures (SOPs) to maintain consistency and quality in my work. I also stay updated with regulatory requirements, such as OECD, GXP, 21 CFR Part 11, EMA, and FDA guidelines, to ensure that our processes meet the highest standards. Regular interactions with Study Directors, Quality Control, and Quality Assurance teams help ensure that my work aligns with regulatory expectations.
Question 3: Could you provide an example of a challenging situation you faced during assay development or analysis, and how you resolved it? Answer : During assay development, I encountered a situation where the assay results showed unexpected variability. After careful troubleshooting, I identified that the variability was due to inconsistent reagent preparation. To address this, I established a stringent protocol for reagent preparation, created a log book to track each step, and implemented a peer-review process. This not only minimized variability but also improved the overall reliability of the assay results.
Question 4: Can you discuss a time when you had to work under tight deadlines and how you managed your time effectively? Answer: Time management is crucial in our field, especially when dealing with time-sensitive studies. Once, we received a request for urgent sample analysis to support a critical decision. To meet the deadline, I organized the tasks, prioritized samples based on their importance, and collaborated closely with the team. By maintaining clear communication and allocating resources efficiently, we successfully completed the analysis and met the deadline without compromising quality.
Question 5: Describe a situation where you had to communicate complex scientific findings to a non-technical audience. How did you ensure effective communication? Answer: Effective communication of scientific findings to non-technical stakeholders is important for informed decision-making. I encountered this while presenting assay data to project managers. I prepared concise visual aids, such as graphs and charts, to illustrate the key results. I focused on explaining the implications of the data in simple terms, highlighting how it aligned with project goals. This approach helped the non-technical audience grasp the significance of the findings and make informed project-related decisions.
Remember that these answers are meant to provide you with a starting point. During the interview, make sure to personalize your responses based on your actual experiences and achievements.
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