SNU - Sponsorship Available
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SNU – Sponsorship Available for the Post-Doctoral Position

SPONSORSHIP AVAILABLE FOR THE POST-DOCTORAL POSITION

Our Lab would like to sponsor positions for the deserving Post Doctorate Fellows (Research
Associate) who wish to apply in my lab. With me as a mentor, the project will be written by the candidate, assisted by me, for applying to the fellowships like DBT-RA, NPDF, WOS, UGCRA, ICMR-RA, INSA/. If and when the project is granted, I will be happy to accommodate the candidate in my Lab and extend all the facilities and knowledge in the fields of Molecular Biology, Protein Chemistry and Virology. Our Lab works on following four projects:

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  1. Development of in vitro HEV Culture system to establish the role of its enzymes and their inhibitors to study the replication cycle of the virus. (DST)
  2. Biochemical and Biophysical characterization of the non-structural enzymes of HEV
    involving their crystallization to find out their inhibitors that may act as putative drug
    candidates. (DBT)
  3. Study the mechanism of processing of HEV polyprotein leading to its cleavage into Nonstructural enzymes. (DST)
  4. Modelling and simulation of the non-structural enzymes to predict the active site and its
    inhibitors using virtual screening ( WOSA)
  5. Finding out cleavage sites on HEV polyprotein by mutagenizing Cysteine protease, the
    digesting enzyme,
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Table of Contents

The PI has Grants worth ~Rs. 2 Crore from DBT, DST and ICMR

Desirable: Person desirous of getting sponsored and working with us should be well versed with techniques in the fields of Biochemistry /Recombinant DNA Technology/Virology as evident from their publications. Please send your CV and Research statement
to [email protected]. If found suitable, I will get in touch subsequently for further discussion.

Our 2020 publication:

Published: Hepatitis E Virus Cysteine Protease has Papain like Properties Validated by insilico Modelling and Cell-free Inhibition Assays Shweta Saraswat1, Meenakshi Chaudhary1, Deepak Sehgal1*
Frontiers in cellular and infection microbiology

Communicated 2020: Development of BacMam Induced Hepatitis E Virus Replication Model in Hepatoma Cells to Study the Polyprotein Processing.
Viruses: Manjeet Kumar1,¶, Preeti Hooda1,¶ Madhu Khanna2, Utkarsh Patel1 and Deepak Sehgal1,*

Communicated 2020 Insights in E64 induced structural changes in Hepatitis E virus protease Meenakshi Chaudhry and Deepak Sehgal.

About Shiv Nadar University:

University is located in Village Chithera, Dadri, Gautam Budh Nagar, 10 Km from Greater
NOIDA. University has made a mark in a very short time and has been selected as one of
the ten private “Institutions of Eminence” by the Government, and the formal notification
is awaited. In the NIRF (Government’s National Institutional Ranking Framework), SNU
has been the youngest institution in the ‘top 100’ Overall list, and our score has been rising
steadily. In NIRF-2019, SNU ranked 52 in the ‘University’ category. We are also among a
select group of green-field institutions in the country which were awarded the prestigious
Atal Incubation Center grant by the Niti Aayog, Government of India, in the very first
round in 2017.

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DEEPAK SEHGAL
PROFESSOR AND HEAD, DEPARTMENT OF LIFE SCIENCES,
SHIV NADAR UNIVERSITY,
CHITHERA, TEHSIL DADRI,
BUDH NAGAR, GREATER NOIDA: 201314

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