Syngene Biotech R&D Jobs
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Syngene Biotech R&D Jobs

MSc & BTech Biotechnology candidates for an R&D position which can be applied for online at Syngene. Syngene is hiring msc & btech biotechnology candidates. Check the details on the positions available, the job description, the key responsibilities, work experience, functional experience all below:

Designation: Downstream Executive

- Advertisement -

ID: 3872

Required Qualification: B.Tech /M.Sc (Biotechnology /Bioengineering/Chemical engineering) with 1-3 yrs industrial experience

Manufacturing and Operation Downstream:

  • The objective of this role as an operator of the downstream manufacturing process at Syngene’s new manufacturing facility for antibodies as well as other
  • Recombinant cell culture products, up to 2000L


These executives roles in the downstream division dedicated production execution

Batch Execution:

  • Know the procedure and execute them according to the BMR instruction
  • Operate the production equipment according to the operating process
  • Understand and develop the experience on the production equipment operation
  • Make sure the batch execution according to the bath plan and execute an error-free operation
  • Ensuring that equipment is in compliance, techniques/systems are implemented and used to meet project targets.
  • Report each of the production deviation and incidence to the supervisors immediately
  • Expect to work proactively involve the production planning

Documentation and GMP Compliance:

  • Make sure the online BMR documentation, GMP compliance in all of the manufacturing activity, and closing of executed documentation.
  • Make sure the conclusion of All of the production-related other documents
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Industrial expertise with international / Indian biopharmaceutical sector at 2000L scale, process scale-up and vulnerability to Single Utilization Bioreactor with comprehension of this saying of monoclonal antibodies and therapeutic proteins.


  • Experience in the purification of recombinant proteins and monoclonal antibodies with a mammalian cell culture system
  • Experience in the purification of monoclonal antibodies in a large-scale operation
  • Exposure to the purification of the vast array of proteins ( novel and biosimilars)
  • Exposure to come up with the strategy for large-scale downstream process
  • Expertise on Scale-up, technology transfer, and purification operation at large scale
  • Expertise in handling downstream process equipment’s like a continuous centrifuge, depth filtration, chromatography system, column chromatography, column packaging and filtration skids
  • Experience in troubleshooting functionality in the protein purification procedure
  • Strong understanding of cGMP operation, quality guidelines and criteria with an ability to interpret and apply them.
  • Expertise and technical knowledge in biologics drug product operations
  • Expertise in writing GMP documents like batch manufacturing records, tech transport document, batch reports, batch analysis and trending, operating process, deviation reports and other associated documents.
  • Proven ability to rapidly adapt to changing environment and conditions requiring flexibility
  • Proficiency using international systems of documentation & enterprise management system (e.g. SAP)
  • Proven skill in demonstrating continuous improvement
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