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Vacancy for Postdoctoral Research Associate @ UCL London and earn upto £40,716  p.a.

The UCL Cancer Institute, Director Professor Tariq Enver is 8years old. The Institute is located in the heart of London, and part of UCL [University College London]. UCL is consistently ranked within the top 20 global universities. The Institute is a purpose-built facility opened in 2008 with state-of-the-art laboratories in the Paul O’Gorman Building housing over 350 scientists involved in cancer prevention, early detection, basic cancer biology and novel therapeutics. There are communal write-up areas with desks, computer and storage space. The Cancer Institute has exceptional core equipment facilities and an active research seminar series. Within the UCL Cancer Institute the position holder will work within the CR-UK DNA-Drug Interactions Research Group. Professors Hartley and Hochhauser work closely in preclinical and clinical studies of innovative agents as well as developing assays for in vivo use to determine effects of these therapies. The Cancer Institute is part of the Faculty of Medical Sciences (UCL School of Life and Medical Sciences) and is the focus for cancer research at UCL with 61 Group leaders, including 48 Faculty members (professorial, reader, and senior lecturers).

Position Title: Post-Doctoral Research Associate in the CRUK Drug-DNA Interactions Research Group

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Main Purpose:

The position seeks a post-doctoral laboratory scientist to undertake research in the field of DNA repair and EGFR pathways. The main aim is to understand the mechanisms by which novel signal transduction inhibitors sensitise cancer cells to chemotherapy and exploit this to improve therapy. The successful candidate should have a background in biological/biomedical science and experience of cellular and molecular biology. Experience in the areas of DNA damage/repair or EGFR would be an advantage.

The post will be based in the Cancer Research UK Drug DNA Interactions Research Group within the UCL Cancer Institute, University College London, UK.

This post will be suitable for candidates experienced in cell biology. This will involve investigation of EGFR internalization following the use of pathway inhibitors and the interaction between EGFR cellular localization and chemotherapy agents. Candidate genes identified by our laboratory as playing a role in this interaction will be investigated to determine potential role in sensitivity to these agents. The duration of this post is 24 months in the first instance. This post is funded in part by a programme grant from CRUK to Professors Hartley and Hochhauser.

Duties and responsibilities:

  • To carry out research on defined, funded project
  • To develop and refine experimental strategies
  • To ensure the validity and reliability of data at all times
  • To analyse and summarise research results and write reports and manuscripts
  • To support and advise other projects in the lab
  • To discuss experimental details, research projects and new articles with lab members
  • To be involved in weekly laboratory meetings
  • To attend research seminars and other meetings, both internal and external, as required
  • To present research results at meetings and conferences
  • To develop contacts and research collaborations within the institute and research fields
  • To assist with other various tasks related to lab management, if and when the need arises
  • To prepare and present findings of research activity to colleagues for review purposes
  • To contribute to, draft and submit of papers to appropriate peer reviewed journals
  • To prepare progress reports on research for funding bodies as required
  • To contribute to the preparation and drafting of research bids and proposals
  • To contribute to the overall activities of the research team and department as required
  • To undertake a limited amount of teaching in relation to subject area
  • To participate in any laboratory duties commensurate with the grade as required
  • To be aware of and act upon:
  1. Disciplinary procedure and Disciplinary rules
  2. Grievance procedure
  3. Section 7 and 8 of the Health and Safety at Work Act
  4. Departmental Fire Guidelines
  5. Equal Opportunities Policy
  6. To comply with the Health & Safety regulations of the department

Person Specifications:

Qualifications:

Essential

PhD in Biological Sciences

Experience:

Essential:

Cell biology, Molecular Biology

Desirable:

HER pathways, EGFR therapeutics, DNA damage/repair assays, Experimental chemotherapy

Essential Skills, Abilities and Knowledge:

  • Computer experience (including Word, Powerpoint, Excel)
  • Good organisational skills and data management
  • Working as part of a team

How to apply:

Apply Online

If you have any queries regarding the advert or the application process please contact:[email protected].

Closing date for receipt of online applications: 31st May, 2016