Postdoctoral Fellow in Mycobacterial Genetics and Systems Biology : EMBL, Hamburg, Germany

The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany) and the outstations are in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy).

• Applications are invited for research projects of the Wilmanns group in the EC-funded consortium SystemTB (www.systemtb.org), which aims to understand the pathology of Mycobacterium tuberculosis during infection. While the core expertise of our group is in structural biology, we have established methods in mycobacterial genetics for the creation of full deletion mutants and specific point mutants using non-pathogenic model systems (M. smegmatis, BCG) (for examples, see: Noens et al. (2011) PMID: 2143903, Poulsen et al. (2010) Mol. Syst. Biol. PMID: 21439037).
• We have initialized several new collaborations using different “–omics” techniques, namely in interactomics (using high throughput mass spectrometry) (IBB Warsaw), metabolomics (ETH Zurich), proteomics (ETH Zurich), and lipidomics (CNRS Toulouse).
• The fellow is expected to carry out and to coordinate experiments in mycobacterial genetics in the context of ongoing and future projects.Most of them will be in cooperation with partners from the SystemTB consortium.