Two Postdoc positions are immediately available at Wang laboratory, Baylor College of Medicine, USA
Two Postdoc positions are immediately available at Wang laboratory, Baylor College of Medicine.
Nature of Work : The individuals will be working on our integrative genomics and functional genomics initiatives aimed at discovering oncogenes, predictive biomarkers and therapeutic targets from next-generation sequencing and genomic data of breast cancer. Candidate will be exposed to state-of-art biotechnologies and receive unique training on bridging cancer biology with genomics, bioinformatics and translational researches. The primary responsibilities of this position are experimental validation of newly discovered cancer genes and targets in breast cancer, confirming their oncogenicity in vitro and in vivo, and elucidating potential clinical applications.
Meanwhile, the candidate may choose to perform genetic screen on 3D cell cultures and in vivo mouse models to discover oncogenes driving endocrine or other therapeutic resistance in breast cancer. This will be done using our newly developed barcoded inducible lentiviral vectors containing selective array of human genes found to be deregulated in breast cancer by genetic or epigenetic aberrations. Candidate can also option to perform integrative bioinformatics analysis of multi-dimensional genomics and sequencing data to discovery new cancer genes and targets.
a. We are looking for highly motivated applicants who have a strong background and hands-on experience in molecular biology and cancer cell biology.
b. Candidate must have a Ph.D. and have less than 2 years of postdoctoral experience in a related field. Preference will be given to those with a outstanding publication record in cancer research, those with established skills on in vivo mice models, or those with additional skill set in bioinformatics and computational biology.